The stem cells and acute respiratory
syndrome: Explored
Featured Products
- Swine Skeletal Muscle Fibroblasts
- Swine Pancreatic Islets Cells
- Swine Lung Alveolar Cells
- Swine kidney Fibroblasts
- Swine Hepatocytes
- Swine Dermal Fibroblats
- Swine Cardiomyocytes
- Swine Cardiac Fibroblasts
- Rat Sprague Dolly Serum Wistar
- Rat Sprague Dolly Serum SD
- Rat Sprague Dolly Serum Immuno-deficient
- Rat Sprague Dolly Plasma Pooled Wistar
- Rat Sprague Dolly Plasma Pooled SD
- Rat Sprague Dolly Plasma Pooled Immuno-deficient
- Rat Sprague Dolly Plasma Female Immuno-deficient
- Rat Schwann Cells Wistar
- Rat Schwann Cells SD
- Rat Schwann Cells Immuno-deficient
- Rat Pulmonary Fibroblasts Wistar
- Rat Pulmonary Fibroblasts SD
- Rat Pulmonary Fibroblasts Immuno-deficient
- Rat Lymphatic Fibroblasts Wistar
- Rat Lymphatic Fibroblasts SD
- Rat Lymphatic Fibroblasts Immuno-deficient
- Rat IGS Serum Wistar
- Rat IGS Serum SD
- Rat IGS Serum SD
- Rat IGS Serum Immuno-deficient
- Rat IGS Plasma Wistar
- Rat IGS Plasma SD
- Rat IGS Plasma Pooled Wistar
- Rat IGS Plasma Pooled SD
- Rat IGS Plasma Pooled Immuno-deficient
- Rat IGS Plasma Immuno-deficient
- Rat Hepatocytes Suspension Wistar
- Rat Hepatocytes Suspension SD
- Rat Hepatocytes Suspension Immuno-deficient
- Rat Hepatocytes Plateable-Wistar
- Rat Hepatocytes Plateable-SD
- Rat Hepatocytes Plateable-Immuno-deficient
- Rat Cardiomyocytes Wistar
- Rat Cardiomyocytes SD
- Rat Cardiomyocytes Immuno-deficient
- Rat Cardiac Fibroblasts Wistar
- Rat Cardiac Fibroblasts SD
- Rat Cardiac Fibroblasts Immuno-deficient
- Rat Brain Vascular Pericytes Wistar
- Rat Brain Vascular Pericytes SD
- Rat Brain Vascular Pericytes Immuno-deficient
- Rat Bone Marrow Derived NK Cells Wistar
- Rat Bone Marrow Derived NK Cells Wistar
- Rat Bone Marrow Derived NK Cells Immuno-deficient
- Rat Bone Marrow Derived Muse Cells Wistar
- Rat Bone Marrow Derived Muse Cells SD
- Rat Bone Marrow Derived Muse Cells Immuno-deficient
- Rat Bone Marrow Derived Muse Cells
- Rat Bone Marrow Derived Mononuclear Cells Wistar
- Rat Bone Marrow Derived Mononuclear Cells Immuno-deficient
- Rat Bone Marrow Derived Mononuclear Cells
- Rat Bone Marrow Derived Mesenchymal Stem Cells Wistar
- Rat Bone Marrow Derived Mesenchymal Stem Cells SD
- Rat Bone Marrow Derived Mesenchymal Stem Cells Immuno Deficient
- Rat Bone Marrow Derived Dendritic Cells Wistar
- Rat Bone Marrow Derived Dendritic Cells SD
- Rat Bone Marrow Derived Dendritic Cells Immuno-deficient
- Primary Human Hepatic Stellate Cells
- Mouse Primary Bone Marrow Derived NK Cells CD1
- Mouse Primary Bone Marrow Derived NK Cells C57
- Mouse Plateable Hepatocytes (CD1)
- Mouse Plateable Hepatocytes (BalbC)
- Mouse NOD SCID Plasma
- Mouse NOD SCID Lung Microsomes Mixed Gender
- Mouse NOD SCID Liver S9 Fraction Mixed Gender
- Mouse NOD SCID Liver Microsomes Mixed Gender
- Mouse NOD SCID Intestinal S9 Fraction Mixed Gender
- Mouse NOD SCID Intestinal Microsomes Mixed Gender
- Mouse NOD SCID Intestinal Cytosol Mixed Gender
- Mouse Muse cells CD1
- Mouse Muse cells C57
- Mouse Muse cells BalbC
- Mouse Lung S9 Fraction Mixed Gender
- Mouse Lung Microsomes Mixed Gender
- Mouse Lung Lysosomes Mixed Gender
- Mouse Lung Cytosol Mixed Gender
- Mouse Liver S9 Fraction Mixed Gender
- Mouse Liver Microsomes Mixed Gender
- Mouse Liver Microsomes Mixed Gender
- Mouse Liver Lysosomes Mixed Gender
- Mouse Liver Cytosol Mixed Gender
- Mouse Intestinal S9 Fraction Mixed Gender
- Mouse Intestinal Microsome Mixed Gender
- Mouse Intestinal Lysosomes Mixed Gender
- Mouse Intestinal Cytosol Mixed Gender
- Mouse Hybrid Plasma
- Mouse Hybrid Lung S9 Fraction Mixed Gender
- Mouse Hybrid Lung Microsomes Mixed Gender
- Mouse Hybrid Lung Lysosomes Mixed Gender
- Mouse Hybrid Lung Cytosol Mixed Gender
- Mouse Hybrid Liver S9 Fraction Mixed Gender
- Mouse Hybrid Liver Microsomes Mixed Gender
- Mouse Hybrid Liver Lysosomes Mixed Gender
- Mouse Hybrid Liver Cytosol Mixed Gender
- Mouse Hybrid Intestinal S9 Fraction Mixed Gender
- Mouse Hybrid Intestinal Microsomes Mixed Gender
- Mouse Hybrid Intestinal Lysosomes Mixed Gender
- Mouse Hybrid Intestinal Cytosol Mixed Gender
- Mouse Hepatocytes Suspension CD1
- Mouse Hepatocytes Suspension C57
- Mouse Hepatocytes Suspension BalbC
- Mouse Hepatocytes Plateable C57
- Mouse Derived Mesenchymal Stem Cells
- Mouse Derived Dendritic Cells
- Mouse DBA S9 Fraction Mixed Gender
- Mouse DBA Plasma
- Mouse DBA Lung S9 Fraction Mixed Gender
- Mouse DBA Lung Microsomes Mixed Gender
- Mouse DBA Lung Lysosome Mixed Gender
- Mouse DBA Lung Cytosol Mixed Gender
- Mouse DBA Liver S9 Fraction Mixed Gender
- Mouse DBA Liver Lysosomes Mixed Gender
- Mouse DBA Liver Cytosol Mixed Gender
- Mouse DBA Intestinal Microsomes Mixed Gender
- Mouse DBA Intestinal Lysosomes Mixed Gender
- Mouse DBA Intestinal Cytosol Mixed Gender
- Mouse Cytosol Mixed Gender
- Mouse Cardiomyocytes CD1
- Mouse Cardiomyocytes C57
- Mouse Cardiomyocytes BalbC
- Mouse Cardiac Fibroblasts CD1
- Mouse Cardiac Fibroblasts C57
- Mouse Cardiac Fibroblasts BalbC
- Mouse C57 BL/6N Plasma
- Mouse C57 BL/6N Lung S9 Fraction Mixed Gender
- Mouse C57 BL/6N Lung Microsomes Mixed Gender
- Mouse C57 BL/6N Lung Lysosomes Mixed Gender
- Mouse C57 BL/6N Lung Cytosol Mixed Gender
- Mouse C57 BL/6N Liver S9 Fraction Mixed Gender
- Mouse C57 BL/6N Liver Microsomes Mixed Gender
- Mouse C57 BL/6N Liver Lysosomes Mixed Gender
- Mouse C57 BL/6N Liver Cytosol Mixed Gender
- Mouse C57 BL/6N Intestinal S9 Fraction Mixed Gender
- Mouse C57 BL/6N Intestinal Microsomes Mixed Gender
- Mouse C57 BL/6N Intestinal Lysosomes Mixed Gender
- Mouse Brain Vascular Pericytes
- Human Umbilical Cord Blood Derived NK cells
- Human Umbilical Cord Blood Derived Mononuclear cells
- Human Umbilical Cord Blood Derived Dendritic Cells
- Human Umbilical Cord Blood Derived CD34+ Cells
- Human T Helper Cells
- Human Splenic Fibroblasts
- Human Splenic Endothelial Cells
- Human Skin S9 Fraction Mixed Gender
- Human Skin Derived Microvascular Dermal Endothelial Cells Adult
- Human Skin Derived Epidermal Melanocytes Fetal
- Human Skin Derived Epidermal Melanocytes Adult
- Human Skin Derived Epidermal Keratinocytes Neonatal
- Human Skin Derived Epidermal Keratinocytes Fetal
- Human Skin Derived Epidermal Keratinocytes Adult
- Human Skin Derived Dermal Fibroblasts Fetal
- Human Skin Derived Dermal Fibroblasts Adult
- Human Serum Peripheral Blood Single Donor
- Human Serum Cord Blood Single Donor
- Human Serum Bone Marrow Single Donor
- Human Seminal vesicles microvascular endothelial cells
- Human Seminal Vesicles Fibroblasts
- Human Seminal Vesicles Endothelial cells
- Human S9 Fraction Heart
- Human S9 Fraction
- Human Pulmonary Small Airway Epithelial Cells
- Human Pulmonary Fibroblasts
- Human Pleatable Hepatocytes Pooled
- Human Plateable Hepatocytes
- Human Plasma Cord Blood Pooled
- Human Plasma
- Human Peripheral Blood-Derived NK Cells
- Human Peripheral Blood-Derived Muse Cells
- Human Peripheral Blood-Derived Mononuclear Cells
- Human Peripheral Blood-Derived Monocytes
- Human Peripheral Blood-Derived Mesenchymal Stem Cells
- Human Peripheral Blood-Derived Cytotoxic T-Cells
- Human Pericardial Fibroblasts
- Human Ovarian Surface Epithelial Cells
- Human Ovarian Fibroblasts
- Human Muse cells
- Human Microvascular Endothelial Cells
- Human Mammary Smooth Muscle Cells
- Human Mammary Fibroblasts
- Human Mammary epithelial cells
- Human Lung S9 Fraction Mixed Gender
- Human Lung Microsomes Mixed Gender
- Human Liver S9 Fraction Mixed Gender
- Human Liver Microsomes Mixed Gender
- Human Liver Microsomes
- Human Kidney Fibroblasts
- Human Islet Beta Cells
- Human Intestine Microsomes Pooled Mixed Gender
- Human Intestinal S9 Fraction Mixed Gender
- Human Hepatocytes in Suspension
- Human Eye Derived Limbal Fibroblasts
- Human Extra Embryonic Fetal Tissues Derived Mesenchymal Stem Cells
- Human Extra Embryonic Fetal Tissues Derived CD34 Positive Cells
- Human Endometrial Epithelial Cells
- Human Dental Pulp Derived Mesenchymal stem cells
- Human Dental Pulp Derived Gingival Fibroblasts
- Human Cytotoxic T Cells
- Human Cardiomyocytes
- Human Cardiac Fibroblasts
- Human Bronchial Fibroblasts
- Human Bone Marrow-Derived NK Cells
- Human Bone Marrow-Derived Mononuclear cells
- Human Bone Marrow-Derived Mesenchymal Stem Cells
- Human Bone Marrow-Derived Dendritic cells
- Human Bone Marrow-Derived CD 34 positive cells
- Human Aortic Smooth Muscle Cells
- Human Aortic Endothelial Cells
- Human Adipose Tissue-Derived Stromal Vascular Fraction
- Human Adipose Tissue-Derived Preadipocytes
- Human Adipose Tissue derived Mesenchymal Stem cells
Drop your Query
The acute respiratory syndromes, majorly affecting the lungs and their efficacy have haunted the world in the last decades with MERS-CoV, SARS-COV, and SARS-CoV-2. Researchers across different corners of the world are trying to understand the relationship between immune dysregulation and disease pathophysiology. While currently, the spread of infection is at major set backstage due to the development of vaccines, scientists are still trying to understand the disease at the cellular and the molecular levels, wherein the cell culture models play a vital role.
We have discovered that primary cells and stem cells can be worked out as excellent cell culture models, possessing the characteristic features of the donors. While our range of cell lines has made a significant contribution during the vaccine development, we are also thrilled to present a range of primary cells, media, and other supportive products for understanding acute respiratory distress syndrome.
So far, 7 different types of coronaviruses have been documented causing acute respiratory distress syndrome; with a different set of genetic heterogeneity and immunological aspects. This genetic complexity coupled with the dwindling supply of antiviral treatment necessitates the need for the development of effective screening and enrichment methods of viruses using suitable in vitro model systems. However, the development of novel vaccines and effective antiviral treatments is currently challenged by multiple issues like batch-to-batch variation, contamination, unavailability of effective primary cells for screening purposes, etc.
At Kosheeka, we believe that it takes the combined efforts of dedicated scientists across the world to discover therapeutic modalities that are needed to maintain the health and safety of humankind. This provokes us to be committed to offering multiple ranges of virus-producing cell lines, primary cells, and stem cells for therapeutic screening.
Accordingly, Kosheeka’s portfolio for acute respiratory distress syndrome includes:
- Range of primary cells for respiratory research, including vascular and microvascular endothelial cells, airway epithelial cells, smooth muscle cells, etc.
- Wide range of primary stem cells to support the therapeutic development of COVID-19, which include mesenchymal stem cells isolated from human umbilical cord Wharton’s jelly. Exosomes isolated from mesenchymal stem cells etc.
- Essential cell culture growth medium for optimized growth and culture.
During the pandemic and in the post-pandemic era, multiple labs and pharmaceutical companies around the globe are relying on our primary cells and stem cells for both vaccine development and development of the therapeutic module.
Stem cell therapy is a significant treatment, applied mainly to COVID-19 during the state of critical vitals; including but not limited to cardiovascular disorders, lung diseases, liver issues, kidney problems, etc. The primary objectives of stem cell therapy are associated with the use of naïve cells from a potent source, culturing them for large-scale production, and restricting them to controlled differentiation in vitro in desired cell types. With the rise in patients complaining of post-COVID complications such as cardiovascular issues, pulmonary disorders, etc. stem cell therapy can be considered as an ideal treatment to repair lung damage.
While configuring the underlying mechanism, studies have confirmed that immune dysregulation is the primary reason for COVID-19 acute infection; which further triggers the release of inflammatory cytokines and antibodies in the patient’s body. This cytokine storm causes symptomatic aggravation, acute cardiac injury, and multiple other secondary infections like generalized sepsis and multisystem failure. The immunoregulatory abilities of mesenchymal stem cells are being extensively studied at multiple levels, confirming their potential in cell-based therapy by regulating both innate as well as adaptive immune functions.
Kosheeka is offering a range of products for therapeutic applications, such as:
- Mesenchymal stem cells isolated from Umbilical Cord Derived Wharton’s jelly
- Mesenchymal stem cells isolated from bone marrow
- Exosomes from mesenchymal stem cells
- NK cells for regulation of immune dysfunctions, in the post-COVID era.
- Liver bile duct progenitor cells were modeled in the 3D form to study liver damage in COVID-19 patients (Zhao et.al; 2020)
- Liver bile duct progenitor cells were modeled in the 3D form to study liver damage in COVID-19 patients (Zhao et.al; 2020)
- Primary gut endothelial stem cells modeled on a pseudostratified layer to study how intestinal epithelium supports SARS-CoV replication (Lamers et.al; 2020)
- Adult human hepatocytes modeled on the 3D system to assess whether these organoids are susceptible to SARS-CoV infection (Yang et.al; 2020)
- Human mesenchymal stem cells derived cardiomyocytes were cultured and studied for androgen signaling pathways (Samuel et.al; 2020)

- Katsura H, Sontake V, Tata A, Kobayashi Y, Edwards CE, Heaton BE, et al. Human lung stem cell-based alveolospheres provide insights into SARS-CoV-2-mediated interferon responses and pneumocyte dysfunction. Cell Stem Cell. 2020;27(6):890–904.
- Lamers MM, Beumer J, van der Vaart J, Knoops K, Puschhof J, Breugem TI, et al. SARS-CoV-2 productively infects human gut enterocytes. Science. 2020;369(6499):50–4.
- Samuel RM, Majd H, Richter MN, Ghazizadeh Z, Zekavat SM, Navickas A, et al. Androgen signaling regulates SARS-CoV-2 receptor levels and is associated with severe COVID-19 symptoms in men. Cell Stem Cell. 2020;27(6):876–89.
- Zhao B, Ni C, Gao R, Wang Y, Yang L, Wei J, et al. Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids. Protein Cell. 2020;11(10):771–5.
- Yang L, Han Y, Nilsson-Payant BE, Gupta V, Wang P, Duan X, et al. A Human pluripotent stem cell-based platform to study SARS-CoV-2 tropism and model virus infection in human cells and organoids. Cell Stem Cell. 2020;27(1):125–36.