In the field of disease biology, cell therapy, and developmental biology, the experimental approaches do not result in reproducible efficiency upon using cell lines as limitations of genetic difference and characterization morphing occur in such cases. Therefore, scientists have shifted towards using primary cells and stem cells for in vitro cell culture studies in order...
In recent times, PDX models or patient-derived xenograft models are getting heavily utilized in head and neck oncology research, specifically for studies on radiation response and organoids. What is a Patient-Derived Xenograft? Patient-derived xenografts (PDX) are xenograft models that have been derived from patient tumor tissues but never adapted to grow like cell line-derived xenografts. Patient-derived...
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