CAR-T cell therapy is a type of treatment where the patient’s T cells are modified in the laboratory for attacking the cancer cells. This type of modification involves adding the gene for a special receptor that binds to a certain cancer cell protein. The special receptor is named CAR or chimeric antigen receptor. CAR-T cell...
Organoids are ex vivo model systems that revolutionized basic and translational cancer research in the domain of disease biology, since last decade. Organoid 3D cultures undergo mitogen-mediated proliferation as multicellular structures in semisolid matrices and while they possess some similarities like 3D spheroid cultures of cell lines, there are basic fundamental differences between them (Tsai...
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