Diabetes is a global concern for the healthcare community. It is a chronic metabolic disorder that can either be Type1 (failure to produce enough insulin) or Type2 (inability of the body to use insulin). The exact cause of Type1 Diabetes is still under research and is believed to be an autoimmune disorder with the involvement...
A crucial step before taking up research work with human or animal tissue is to ensure appropriate ethical and medical legislation and guidelines for experiments. This can also deal with procuring approval from relevant authorities or individuals. Biohazards and Safety considerations It is very important to know the possible associated risks while working with potential...
Mesenchymal stem cells (MSCs) are multipotent adult stem cells. Being mutipotent, MSCs can differentiate into more than one specialized cell of the body. Generally, MSCs make the different cells in skeletal tissues e.g., chondrocytes, osteoblast, adipocyte etc. In case of MSCs giving rise to other specialized cells like neurons, reprogramming of the cells with gene...
Biomedical research advancements depend on data credibility but scientific results are not always reproducible. Independent verification of cell culture findings is a basic principle of research and the procedure and other factors affect the concept of research reproducibility heavily. Many scientists who work with primary cell culture focus on the ‘correctness’ of the results but...
In the field of biomedical research, 2D cell cultures have extensively been used since the early 1900s but in recent times, the technology of 3D cell culture has boomed. The tussle of 2D vs 3D cell culture has received much interest from biomedical researchers and other science geeks. In this article, let us explore more...
A good biomedical research paper writing (review or research paper) requires an intensive literature search for information pertaining to the study, whether it involves primary cell culture or microbial studies. This literature survey takes into account rigorous searching and compiling of all previous studies and data on a particular topic. The literature survey helps further...
In order to minimize problems of misidentification that can lead to research being retracted and the loss associated due to contamination. The following pointers can be used as a reminder to facilitate good practices for primary cultures in biomedical research: The derivation of culture from fresh human tissue involves the first step of obtaining ethical...
3D cell culture has been a boon to the scientific community for cell culture experiments and is extensively used as an alternative to in vivo animal experiments. 3D cell culture presents itself as an assembly of cells that mimics tissue-specific / organ-specific architecture. 2D cell culture is the most common cell culture practice in vitro...
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