Extra Embryonic Fetal Tissue Derived Stem Cells

Umbilical Cord Blood Derived Dendritic Cells

Ethically sourced from human umbilical cord tissue, dendritic cells exhibit exceptional potency in stimulating the immune system; making them ideal candidates for immunological research or advanced therapeutic models. These cells serve as vital research tools in cancer immunotherapy, where they can be loaded with tumor antigens to express key surface markers essential for antigen presentation and immune activation.At Kosheeka, we are making sure that each batch is carefully isolated and quality checked for specific parameters like surface markers including CD11C+, CD86+, CD80+, HLA DR+, and CD14- to provide detailed characterization of the cells. These cells can multiply and survive in the specific culture media with proper growth factors and cytokines, for up to 7 days, and can be maintained as immature dendritic cells. Further differentiation to mature dendritic cells can be facilitated, with the addition of differentiation cocktails (TNF-alpha and IL-1Beta).Thus, each vial of cryopreserved dendritic cells contains 1-2 million cells. The surface marker expression levels are tested for above-mentioned CD11C+, CD86+, CD80+, HLA DR+, and CD14- markers, and the information of the same is provided along with the certificate of analysis.

Muse Cells

These are the adult stem cells that are commonly found in tissue sources like bone marrow, peripheral blood and cord blood. The cells exhibit unique multilineage transdifferentiation potential and remarkable self-renewal potential. The cells are highly recognized for their resistance to stress without forming tumors; due to which they are used in multiple disciplines of regenerative medicine.At Kosheeka, we have standardized the isolation technique of MUSE cells using a cocktail of cytokines and growth factors. With appropriate culture conditions, these cells are allowed to adhere to the plastic surface of the coated flask and form colony-like structures. The cells are characterized by several distinct markers including CD105, SSEA-3, etc. One has to be very careful during culturing these cells, due to their spontaneous differentiation capacity into cells of other tissues.