Primary Cells

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Application of Primary Cells

Drug screening and toxicity evaluation

Primary cells can find its wide application in pharmaceutical industry. Primary cell cultures can be used to evaluate maximum permissible drug dosage and toxicity of drugs.

In vitro model to study Cell biology and metabolic studies

Because of its resemblance to natural and living environment, they can be used as model system to study cell biology, metabolic regulations.

As a substitute for animal studies

Use of primary cell line can reduce the cost of animal experiments.

Tissue Engineering and Regenerative medicine

Currently, researchers are exploring the usage of primary cells in the reconstruction of diseased or damaged tissue or organs.

Advantages of Primary Cells

Closely mimics in vivo conditions

Primary cells closely stimulate biological living model thus provide significant and high quality results in experiments

Minimal chromosomal aberrations

The Major disadvantage with established cell line is that after a period, cell characteristics may change and become quite different from initial passages. Generally primary cells not only retain normal physiology but also genetic constitution when propagated in culture.

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