Organoids are tiny, self-organized three-dimensional tissue cultures that are derived from stem cells. Such cultures can be crafted to replicate much of the complexity of an organ, or to express selected aspects of it like producing only certain types of cells. There are potentially as many types of organoids as there are different tissues and organs in the body. To date, researchers have been able to produce organoids that resemble the brain, kidney, lung, intestine, stomach, and liver, and many more are on the way. This way of culturing tissues will give scientists a detailed view of how organs form and grow, providing them with new insights on human development and disease as well as giving them the opportunity to see how drugs interact with these “mini-organs”, potentially revolutionizing the field of drug discovery and opening new approaches to personalized medicine.
Presented By Dr. Sivarajan T, Ex-Scientist, The John Hopkins University, USA. Dr. Sivarajan T has pursued his post doctoral from The John Hopkins University, USA and has been a senior scientist in the R&D of Pandorum Technologies Pvt. Ltd. His interest lies in 3D bioprinted tissue handling, liver organoids, transgenic mice work, drug toxicity studies in vivo and in vitro and imaging.
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