Mesenchymal stem cells for TB Not only is tuberculosis (TB) among the top 10 causes of death in the world but it also is the leading cause of death due to a single infectious agent! Though curable and preventable, close to 10 million people (5.7 million men, 3.2 million women and 1.1 million children) contracted...
Mesenchymal Stem Cells for the treatment of Crohn’s disease Crohn’s disease (CD) is an inflammatory bowel disease involving chronic inflammation of any part of the gastrointestinal tract. The disease incidence is on the rise across the globe with the exact cause behind still being explored by research. There is a wide range of factors involved...
According to the World Health Organization (WHO), dementia is mainly seen in older people though it is not normally part of the aging process. There is a decline in thinking, memory, behavior, and the ability to perform everyday activities. Across the globe, there are 10 million new cases every year of dementia with the most...
According to a study by the GBD Chronic Kidney Disease Collaboration (2020), the incidence of chronic kidney disease (CKD) was 697·5 million or 9.1% in 2017: an increase of 29·3% from what was reported in 1990. The loss of lives due to CKD increased by 41·5% between 1990 and 2017! CKD is a risk factor...
One of the major causes of acute kidney injury (AKI) is sepsis: this becomes significant given that 1–35% of hospitalized patients develop AKI. In the case of general surgery, the incidence of AKI is close to 1% but this figure reaches a whopping 70% for critically ill patients accounting for in-hospital mortality of 50% in...
Sepsis refers to the loss of regulation of the host response to an infection. Not only is it considered the most frequent cause of death in hospitalized patients but it also accounts for an expenditure of US$24 billion per year. According to a study published in 2020 by scientists Rudd and team, close to...
Researchers Friedenste in and his collaborators first described MSCs or mesenchymal stem cells as cells that could differentiate into other lineages and were adherent to plastic. They have generated much interest among researchers to explore the use of these cells for treating diseases or pain relief on account of their ease of isolation from a...
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