In vitro cell culture systems have been considered as essential research tools for biomedical and clinical research and development. Although it started with 2D cell culture consisting of cell monolayers, the recent practice of cell culture, specifically for primary cell culture, advanced 3D in vitro culture systems are widely being adopted for the advantages of...
Primary cells culture refer to the removal of tissue from an organism and maintaining them in an appropriate medium to allow their division. One approach involves placing a piece of tissue in a glass or plastic vessel followed by bathing it in a medium. Division and growth of primary cell occur when cells separate from...
With an increasing need for extensive research on SARS-CoV2 biology, the diagnosis of COVID-19 infections by cell culture relies heavily on the careful and aseptic collection of specimens. This is where specialized Viral Transport Medium (VTM) is required to protect the virus from environmental damage and maintain its activity with adequate sustainable transport system. Over...
Drug discovery and development extensively drives biomedical research and primary cell culture has been a very important turning point for the drug development domain. Along with primary cell culture, a critical factor in drug discovery is the study of biomarkers. The quality of biomarker detection encourages and enhances the efficiency of drug target identification, biological...
Researchers Friedenste in and his collaborators first described MSCs or mesenchymal stem cells as cells that could differentiate into other lineages and were adherent to plastic. They have generated much interest among researchers to explore the use of these cells for treating diseases or pain relief on account of their ease of isolation from a...
According to a population-based estimate (2019), 300,000 to 400,000 individuals are affected by multiple sclerosis (MS): the most common progressive neurologic disease in the United States. The disease is considered a chronic inflammatory disease of the central nervous system (CNS) that leads to demyelination and axonal loss. The disease is complex and multi-factorial with the...
The immunomodulatory properties of Mesenchymal Stem Cells (MSCs) coupled with their isolation from several sources ranging from bone marrow to adipose tissue to umbilical cord to placenta to dental pulp, and even menstrual fluid makes them attractive options for use in cell-based therapy. According to the National Institute of Environmental Health Sciences, autoimmune diseases affect...
Apart from serving as a source of food, pigs are considered as the ideal models of modeling human diseases. This arises from the similarity in their anatomy and physiology with that of humans. The pig genome is three times closer to our genome that that of mice. Take the example of cystic fibrosis, the introduction...
The idea that adipose tissue is a reservoir of heat and an energy source has been changed with research highlighting the tissue involved in intricate interactions with other systems of our body: cardiovascular, nervous and endocrine systems. A secretome attributed to the adipose tissue or adipose mesenchymal stem cells that includes growth factors and adipocytokines...
Close to 35 million men in the United States face some issue of hair losswith close to 21 million women are affected by hair loss, according to a 2014 survey by the International Society of Hair Restoration Surgery (http://www.statisticbrain.com/hair-loss-statistics/). One of the most common hair loss manifestations is androgenic alopecia that targets 30 to 50%...
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