3D Bioprinting For Medical Applications

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3D Bioprinting for Medical Applications

Bioprinting is an additive biomanufacturing process where biomaterials, primary cells or stem cells, and bioactive factors are combined in the form of bio-ink and printed in a layer-by-layer manner to create tissue-like structures. Based on the operation, this technology can be classified into three major categories, inkjet-based, extrusion-based, and laser-assisted bioprinting. Applications of 3D bioprinting, both actual and potential, can be categorized into several broad classes, including tissue and organ fabrication; creation of customized prosthesis, and implants; development of anatomical and surgical models; construction of in vitro tissue/organ/cancer model and pharmaceutical research involving drug dosage forms, delivery, and discovery. The application of 3D bioprinting in medicine brings in many benefits, including the customization and personalization of medical products, drugs, and equipment; cost-effectiveness; increased productivity; the democratization of design and manufacturing; and enhanced collaboration. However, it should be cautioned that outstanding scientific and regulatory challenges remain and the most transformative applications for this technology are yet to be fully realized. This talk focuses on different aspects of this technology along with the examples taken from various case studies and research endeavors.

Presented by Prof. Falguni Pati, Associate Prof. in the Biomedical Engineering Department at IIT Hyderabad. Prof. Pati received his Ph.D. from IIT Kharagpur and has had Postdoctoral appointments in POSTECH, South Korea, and KTH, Stockholm, Sweden. His Biofabrication and Tissue Engineering (BioFabTE; https://biofablab-com.webnode.com) Lab at IIT H focuses on developing innovative tissue-engineered products and in vitro tissue/organ models with 3D bioprinting technology. His research interests include developing novel bio-ink, bioprinting methods and protocol for the production of tissue analogs-on-demand, and in vitro tissue/organ models with funding from the MHRD, DST-SERB, and DBT. Besides being the recipient of many awards including the prestigious Ramalingaswami fellowship, Dr. Pati has filed three Indian and one US patent, authored over 25 journal papers, 10 book chapters, and one book.

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